Survival Analysis Sample Size Calculation

Survival Analysis Sample Size Calculator




Introduction & Importance

Survival analysis sample size calculation is a critical step in designing clinical trials…

How to Use This Calculator

  1. Enter the desired significance level (α).
  2. Enter the desired power (1 – β).
  3. Choose an effect size.
  4. Click “Calculate”.

Formula & Methodology

The sample size calculation is based on the formula…

Real-World Examples

Data & Statistics

Comparison of Sample Sizes
Effect Size α = 0.05, Power = 0.8 α = 0.05, Power = 0.9
0.2 186 246
0.3 87 115
0.4 45 59

Expert Tips

  • Consider using a higher power for rare diseases.
  • Adjust the effect size based on the expected treatment effect.

Interactive FAQ

What is the default effect size?

The default effect size is 0.3.

Can I change the significance level?

Yes, you can change the significance level (α) to any value between 0.01 and 0.1.

FDA Guidance on Sample Size for Clinical Trials

NCI: Sample Size in Clinical Trials

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